No-Spa Tablets 40mg 20’s Uses Side Effects Dose Price In Pakistan

 No-Spa Tablets 40mg 20’s Uses Side Effects Dose Price In Pakistan

 Composition

NO-SPA 40mg tablet contains 40mg of drotaverine hydrochloride.

 No-Spa Tablets 40mg 20’s Uses Side Effects Dose Price In Pakistan

Smooth muscle spasms connected with diseases of biliary origin, cholecystolithiasis, cholangiolithiasis, cholecystography, cholecystitis, pericholecystitis, Cholangitis Papillitis.

Smooth muscle spasm of the urinary tract: Nephrolithiasis, Ureterolithiasis, Pyelitis.

Cystitis, vesical tenesmus.

As adjuvant
Smooth muscle spasms of gastrointestinal origin: gastric and duodenal ulcer, gastric enteritis, colitis and pylorus spasm, irritable colon syndrome, spastic constipation, or gas syndrome, pancreatitis. Headaches of vascular origin. In gynecological diseases: dysmenorrhoea, adnexitis.
For injection
Smooth muscle spasms connected with diseases of biliary origin, cholecystolithiasis, cholangiolithiasis, cholecystitis, pericholecystic, cholangitis papillote. Smooth muscle spasms of the urinary tract: nephrolithiasis, ureterolithiasis, pyelitis, cystitis, cramps of the urinary bladder.
As adjuvant
In smooth muscle spasms of gastrointestinal origin: gastric and duodenal ulcer, gastritis, cardiac and pylorus spasm, enteritis, and colitis.
In Gynecological diseases: dysmenorrhoea.
Dosage and administration
For tablets
Children between 1 and 6 years: The usual daily dose is 40-120mg (in 2-3 divided doses).
Children over 6 years: The usual daily dose is 80-200mg (in 2-5 divided doses).
Adults: The usual daily dose is a 120-240mg daily (in 2-3 divided doses).
For injection
Adults: The usual daily dose is 40-240mg (in 1-3 parts) I.M.
In acute stone colic(renal and/or biliary) 40-80mg I.V.
Special populations:
Children: The use of Drotaverine in children has not been evaluated in clinical studies.

No-Spa Tablets 40mg 20’s Contraindications:

– Hypersensitivity to the active ingredient or to any of the excipients (such as soy lecithin)
– Severe renal or hepatic failure
– Severe cardiac insufficiency (low output syndrome)
– Children under 1- year old.
For injection
– Hypersensitivity to the active ingredient or to any of the excipients
– Hypersensitivity to sodium disulfites (see section precautions).
– Severe renal or hepatic failure.
– Severe cardiac insufficiency (low output syndrome)
– Children
Precautions
For tablets
In hypotension, the administration of this drug needs increased caution.
Due to the presence of lactose, patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption should not take this medicine.
The use of drotaverine in Children has not been evaluated in clinical studies.
For injection
 In case of hypotension, the administration of this drug needs increased caution. When administered by IV rote, the patient should be strictly in recumbent position due to the risk of collapse l.
 This product contains disulfites, which can cause allergic-type reactions including anaphylactic symptoms and bronchospasm in susceptible people, especially those with a history of asthma or allergy.
* In case of Hypersensitivity to sodium disulfites parenteral administration of the drug should be avoided (see Contraindications).
Caution should be exerted when administering injection drotaverine in pregnant women (see pregnancy).

NO-SPA Tablets Interactions:

Phosphodiesterase inhibitors like papaverine decrease the antiparkinsonian effect of levodopa. When drotaverine is administered together with levodopa, rigidity and tremor may, therefore, become aggravated.
Pregnancy:
A limited amount of data on pregnant patients is available. Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy and embryonal/fetal development. Nevertheless, caution should be taken when prescribing to pregnant women.
Lactation: The excretion of drotaverine in milk has not been studied in animals. Therefore, its administration during breastfeeding Is not recommended.
Driving a vehicle or performing other hazardous tasks: Patients should be instructed that if they experience vertigo, they should avoid potentially hazardous tasks such as driving or operating machines.

NO-SPA Tablets 40mg Adverse Reaction:

The following CIOMS frequency rating is used, when applicable: very common >10% common >1 and <10%; uncommon >0.1and <1% Rare >0.01 and < 0.1% very rare <0.01% Not Known (cannot be estimated from available data).
Cardiac disorders
Rare: palpitations. Hypotension.
Nervous system disorders
Rare: headache. Vertigo, insomnia.
Gastrointestinal disorders
Rare: nausea, constipation.
Immune system disorders
Rare: allergic (angioedema, urticaria, rash, pruritus) (see section Contraindications) Not Known: fatal and non-fatal anaphylactic shock have been reported in patients treated with the injectable form.
General disorders and administration site conditions
Injection site reaction (for injectable form only).

 Overdosage

Signs and symptoms: Drotaverine overdose has been associated with heart rhythm and conduction disorders including complete bundle branch block and cardiac arrest, which may be fatal.
Management:
I. the Case of drotaverine, the patient should be closely monitored, and managed by symptomatic and supportive care.

NO-SPA TABLETS 40mg price in Pakistan

No-Spa Tablets 40mg 20′ price in Pakistan is 160 rupees.

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